MolNFT v1 · #42720 · protein
Solution structure of human sodium/ hydrogen exchange regulatory factor 1(150-358)
2KRG · NA(+)/H(+) exchange regulatory cofactor nhe-RF1: “Solution structure of human sodium/ hydrogen exchange regulatory factor 1(150-358)”. Solution nmr, 2 pockets (best druggability 0.52). MolNFT v1 #42720 on GenesisL1: 3D structure…
- PDB
- 2KRG
- Type
- protein
- Length
- 216 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- NA(+)/H(+) exchange regulatory cofactor nhe-RF1
- UniProt
- O14745
- Pockets
- 2 · best druggability 0.52
Structure
solution nmr · 1 distinct chain · 19% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NA(+)/H(+) exchange regulatory cofactor nhe-RF1 | protein | 216 | 19% helix, 12% strand | O14745 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 188 | 0.52 | 0.78 | 24 | empty |
| 2 | 87 | 0.44 | 0.80 | 15 | empty |
Compared structures
- 2KRG · Solution Structure of human sodium/ hydrogen exchange regulatory factor 1(150-358) · the same entry in another collection · chain A against A, TM-score 1.00
- O14745 · AlphaFold monomer V2.0 prediction for NA(+)/H(+) exchange regulatory cofactor nhe-RF1… · a predicted model of the same protein · chain A against A, TM-score 0.91
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O14745
- Elsewhere: RCSB PDB 2KRG · PDBe 2KRG · UniProt O14745
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