MolNFT v1 · #42705 · protein
Solution structure of the proteasome ubiquitin receptor RPN13
2KR0 · Proteasomal ubiquitin receptor ADRM1: “Solution structure of the proteasome ubiquitin receptor RPN13”. Solution nmr, 2 pockets (best druggability 0.61). MolNFT v1 #42705 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2KR0
- Type
- protein
- Length
- 407 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Proteasomal ubiquitin receptor ADRM1
- UniProt
- Q16186
- Pockets
- 2 · best druggability 0.61
Structure
solution nmr · 1 distinct chain · 24% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Proteasomal ubiquitin receptor ADRM1 | protein | 407 | 24% helix, 12% strand | Q16186 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 396 | 0.61 | 0.77 | 49 | empty |
| 2 | 60 | 0.28 | 0.73 | 12 | empty |
Compared structures
- 2KR0 · Solution structure of the proteasome ubiquitin receptor Rpn13 · the same entry in another collection · chain A against A, TM-score 1.00
- Q16186 · AlphaFold monomer V2.0 prediction for proteasomal ubiquitin receptor ADRM1 (Q16186) · a predicted model of the same protein · chain A against A, TM-score 0.31
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q16186
- Elsewhere: RCSB PDB 2KR0 · PDBe 2KR0 · UniProt Q16186
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