MolNFT v1 · #42581 · protein

Structure of full-length human asc (apoptosis-associated speck-like protein containing a card)

2KN6: “Structure of full-length human asc (apoptosis-associated speck-like protein containing a card)”. Solution nmr, 1 pocket (best druggability 0.37). MolNFT v1 #42581 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2KN6
Type: protein
Length: 195 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Apoptosis-associated speck-like protein containing a card
UniProt: Q9ULZ3
Pockets: 1 · best druggability 0.37

Structure

solution nmr · 1 distinct chain · 66% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Apoptosis-associated speck-like protein containing a card	protein	195	66% helix, 0% strand	Q9ULZ3

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	64	0.37	0.77	13	empty

Compared structures

2KN6 · Structure of full-length human ASC (Apoptosis-associated speck-like protein containing a… · the same entry in another collection · chain A against A, TM-score 1.00
Q9ULZ3 · AlphaFold monomer V2.0 prediction for apoptosis-associated speck-like protein containing… · a predicted model of the same protein · chain A against A, TM-score 0.45

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9ULZ3
Elsewhere: RCSB PDB 2KN6 · PDBe 2KN6 · UniProt Q9ULZ3

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