MolNFT v1 · #42420 · protein

Solution structure of myosin VI C-terminal cargo-binding domain

2KIA · Myosin-VI: “Solution structure of myosin VI C-terminal cargo-binding domain”. Solution nmr, 1 pocket (best druggability 0.36). MolNFT v1 #42420 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2KIA
Type: protein
Length: 129 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Myosin-VI
UniProt: Q64331
Pockets: 1 · best druggability 0.36

Structure

solution nmr · 1 distinct chain · 35% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Myosin-VI	protein	129	35% helix, 27% strand	Q64331

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	88	0.36	0.75	24	empty

Compared structures

2KIA · Solution structure of Myosin VI C-terminal cargo-binding domain · the same entry in another collection · chain A against A, TM-score 1.00
Q64331 · AlphaFold monomer V2.0 prediction for unconventional myosin-VI (Q64331) · a predicted model of the same protein · chain A against A, TM-score 0.80

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q64331
Elsewhere: RCSB PDB 2KIA · PDBe 2KIA · UniProt Q64331

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