UniProt Q64331
Unconventional myosin-VI (Q64331)
Unconventional myosin-VI (UniProt Q64331): 8 experimental structures and 1 predicted model on GenesisL1, 31 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q64331
- Protein
- Unconventional myosin-VI
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 31 · 3 records with a druggable one
Structures
9 records of Q64331 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2KIA | Solution structure of Myosin VI C-terminal cargo-binding domain | solution nmr | A | — | — |
| 2KIA | Solution structure of myosin VI C-terminal cargo-binding domain | solution nmr | A | — | — |
| 3H8D | Crystal structure of Myosin VI in complex with Dab2 peptide | x-ray diffraction | A, B, C, D | — | — |
| 3H8D | Crystal structure of myosin VI in complex with DAB2 peptide | x-ray diffraction | A, B, C, D | — | — |
| 5V6E | Crystal structure of Myosin VI in complex with GH2 domain of GIPC1 | x-ray diffraction | B, D, F, H, J | — | 8 (best 0.58) |
| 5V6E | Crystal structure of myosin VI in complex with GH2 domain of GIPC1 | x-ray diffraction | B, D, F, H, J | — | — |
| 5V6H | Crystal structure of Myosin VI in complex with GH2 domain of GIPC2 | x-ray diffraction | B, D, F, H, J | — | 9 (best 0.53) |
| 5V6H | Crystal structure of myosin VI in complex with GH2 domain of GIPC2 | x-ray diffraction | B, D, F, H, J | — | — |
| Q64331 | AlphaFold monomer V2.0 prediction for unconventional myosin-VI (Q64331) | predicted | A | — | 14 (best 0.78) |
Experiment against prediction
- 3H8D chain D against the predicted model Q64331: TM-score 0.90, RMSD 1.44 Å
- 3H8D chain D against the predicted model Q64331: TM-score 0.90, RMSD 1.44 Å
- 3H8D chain A against the predicted model Q64331: TM-score 0.90, RMSD 1.83 Å
- 3H8D chain A against the predicted model Q64331: TM-score 0.90, RMSD 1.83 Å
- 5V6H chain D against the predicted model Q64331: TM-score 0.90, RMSD 0.72 Å
- 5V6H chain B against the predicted model Q64331: TM-score 0.88, RMSD 0.80 Å
- 5V6H chain B against the predicted model Q64331: TM-score 0.88, RMSD 0.80 Å
- 3H8D chain B against the predicted model Q64331: TM-score 0.87, RMSD 1.50 Å
- 3H8D chain B against the predicted model Q64331: TM-score 0.87, RMSD 1.50 Å
- 3H8D chain C against the predicted model Q64331: TM-score 0.87, RMSD 1.84 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.