MolNFT v1 · #42398 · protein
NMR solution structure of the eh 1 domain from human intersectin-1 protein. northeast structural genomics consortium target HR3646E.
2KHN: “NMR solution structure of the eh 1 domain from human intersectin-1 protein. northeast structural genomics…”. Solution nmr, 3 pockets (best druggability 0.40). MolNFT v1 #42398 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 2KHN
- Type
- protein
- Length
- 121 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Intersectin-1
- UniProt
- Q15811
- Pockets
- 3 · best druggability 0.40
Structure
solution nmr · 1 distinct chain · 43% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Intersectin-1 | protein | 121 | 43% helix, 0% strand | Q15811 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 117 | 0.40 | 0.75 | 21 | empty |
| 2 | 75 | 0.38 | 0.78 | 18 | empty |
| 3 | 61 | 0.31 | 0.75 | 12 | empty |
Compared structures
- 2KHN · NMR solution structure of the EH 1 domain from human intersectin-1 protein. Northeast… · the same entry in another collection · chain A against A, TM-score 1.00
- Q15811 · AlphaFold monomer V2.0 prediction for intersectin-1 (Q15811) · a predicted model of the same protein · chain A against A, TM-score 0.68
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q15811
- Elsewhere: RCSB PDB 2KHN · PDBe 2KHN · UniProt Q15811
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