MolNFT v1 · #42277 · protein

Solution structure of RNA pyrophosphohydrolase rpph from escherichia COLI

2KDV: “Solution structure of RNA pyrophosphohydrolase rpph from escherichia COLI”. Solution nmr, 1 pocket (best druggability 0.42). MolNFT v1 #42277 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2KDV
Type: protein
Length: 164 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: RNA pyrophosphohydrolase
EC: 3.6.1.-
UniProt: P0A776
Pockets: 1 · best druggability 0.42

Structure

solution nmr · 1 distinct chain · 28% helix, 31% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	RNA pyrophosphohydrolase (EC 3.6.1.-)	protein	164	28% helix, 31% strand	P0A776

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	153	0.42	0.74	23	empty

Compared structures

2KDV · Solution structure of RNA Pyrophosphohydrolase RppH from Escherichia coli · the same entry in another collection · chain A against A, TM-score 1.00
P0A776 · AlphaFold monomer V2.0 prediction for RNA pyrophosphohydrolase (P0A776) · a predicted model of the same protein · chain A against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0A776
Elsewhere: RCSB PDB 2KDV · PDBe 2KDV · UniProt P0A776

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