MolNFT v1 · #42270 · protein
Structure of the human shwachman-bodian-diamond syndrome protein, sbds
2KDO · Ribosome maturation protein sbds: “Structure of the human shwachman-bodian-diamond syndrome protein, sbds”. Solution nmr, 5 pockets (best druggability 0.53). MolNFT v1 #42270 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 2KDO
- Type
- protein
- Length
- 252 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ribosome maturation protein sbds
- UniProt
- Q9Y3A5
- Pockets
- 5 · best druggability 0.53
Structure
solution nmr · 1 distinct chain · 33% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ribosome maturation protein sbds | protein | 252 | 33% helix, 19% strand | Q9Y3A5 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 91 | 0.53 | 0.84 | 20 | empty |
| 2 | 158 | 0.50 | 0.78 | 23 | empty |
| 3 | 153 | 0.46 | 0.76 | 19 | empty |
| 4 | 92 | 0.40 | 0.77 | 19 | empty |
| 5 | 78 | 0.34 | 0.76 | 16 | empty |
Compared structures
- 2KDO · Structure of the human Shwachman-Bodian-Diamond syndrome protein, SBDS · the same entry in another collection · chain A against A, TM-score 1.00
- Q9Y3A5 · AlphaFold monomer V2.0 prediction for ribosome maturation protein sbds (Q9Y3A5) · a predicted model of the same protein · chain A against A, TM-score 0.43
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y3A5
- Elsewhere: RCSB PDB 2KDO · PDBe 2KDO · UniProt Q9Y3A5
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