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Structure of the human shwachman-bodian-diamond syndrome protein, sbds

Analyse Structure of the human shwachman-bodian-diamond syndrome protein, sbds in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2KDO
Type
protein
Length
252 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Ribosome maturation protein sbds
UniProt
Q9Y3A5
Pockets
5 · best druggability 0.53

Structure

solution nmr · 1 distinct chain · 33% helix, 19% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ARibosome maturation protein sbdsprotein25233% helix, 19% strandQ9Y3A5

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1910.530.8420empty
21580.500.7823empty
31530.460.7619empty
4920.400.7719empty
5780.340.7616empty

Compared structures

  • 2KDO · Structure of the human Shwachman-Bodian-Diamond syndrome protein, SBDS · the same entry in another collection · chain A against A, TM-score 1.00
  • Q9Y3A5 · AlphaFold monomer V2.0 prediction for ribosome maturation protein sbds (Q9Y3A5) · a predicted model of the same protein · chain A against A, TM-score 0.43

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