MolNFT v1 · #42182 · protein

CDC42(T35A)

2KB0 · Cell division control protein 42 homolog: “CDC42(T35A)”. Solution nmr, 4 pockets (best druggability 0.81). MolNFT v1 #42182 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2KB0
Type: protein
Length: 178 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cell division control protein 42 homolog
UniProt: P60953
Pockets: 4 · best druggability 0.81

Structure

solution nmr · 1 distinct chain · 33% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cell division control protein 42 homolog	protein	178	33% helix, 20% strand	P60953

Pockets

4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	366	0.81	0.90	43	empty
2	455	0.75	0.83	51	empty
3	71	0.53	0.86	21	empty
4	146	0.48	0.78	23	empty

Compared structures

2KB0 · Cdc42(T35A) · the same entry in another collection · chain A against A, TM-score 1.00
P60953 · AlphaFold monomer V2.0 prediction for cell division control protein 42 homolog (P60953) · a predicted model of the same protein · chain A against A, TM-score 0.79

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P60953
Elsewhere: RCSB PDB 2KB0 · PDBe 2KB0 · UniProt P60953

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