MolNFT v1 · #4216 · protein
Crystal structure of adenosine kinase from toxoplasma gondii
1DGM: “Crystal structure of adenosine kinase from toxoplasma gondii”. X-ray diffraction, 3 ligands (ADN, MG, CL), 1 pocket (best druggability 0.71). MolNFT v1 #4216 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1DGM
- Type
- protein
- Length
- 346 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Adenosine kinase
- EC
- 2.7.1.20
- UniProt
- Q9TVW2
- Ligands
- ADN, MG, CL
- Pockets
- 1 · best druggability 0.71
Structure
x-ray diffraction · 1 distinct chain · 40% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Adenosine kinase (EC 2.7.1.20) | protein | 346 | 40% helix, 24% strand | Q9TVW2 |
Ligands and binding sites
- ADN · Adenosine · ligand · chains A
- MG · Magnesium ion · metal · chains A
- CL · Chloride ion · ion · chains A
- ACY · Acetic acid · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 630 | 0.71 | 0.79 | 65 | CL, ADN, ACY |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9TVW2
- Elsewhere: RCSB PDB 1DGM · PDBe 1DGM · UniProt Q9TVW2
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