GL1X · GenesisL1 explorer

MolNFT v1 · #42158 · protein

NMR structure of the cbp-TAZ2/STAT1-tad complex

2KA6 · Creb-binding protein: “NMR structure of the cbp-TAZ2/STAT1-tad complex”. Solution nmr, 1 ligand (ZN). MolNFT v1 #42158 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
2KA6
Type
protein
Length
137 residues
Chains
2
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Creb-binding protein; Signal transducer and activator of transcription 1- ALPHA/BETA
EC
2.3.1.48
UniProt
P45481, P42224
Ligands
ZN

Structure

solution nmr · 2 distinct chains · 53% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ACreb-binding protein (EC 2.3.1.48)protein9263% helix, 0% strandP45481
BSignal transducer and activator of transcription 1- ALPHA/BETAprotein4531% helix, 0% strandP42224

Ligands and binding sites

  • ZN · Zinc ion · metal · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

  • A–B · 1588 Ų buried · 22 hydrogen bonds · protein-protein

Compared structures

  • 2KA6 · NMR structure of the CBP-TAZ2/STAT1-TAD complex · the same entry in another collection · chain A against A, TM-score 1.00
  • P45481 · AlphaFold monomer V2.0 prediction for histone lysine acetyltransferase crebbp (P45481) · a predicted model of the same protein · chain A against A, TM-score 0.90
  • P42224 · AlphaFold monomer V2.0 prediction for signal transducer and activator of transcription… · a predicted model of the same protein · chain B against A, TM-score 0.42

Analyse

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.