MolNFT v1 · #42086 · protein

Human arnt C-terminal pas domain, 3 residue ib slip

2K7S · Aryl hydrocarbon receptor nuclear translocator: “Human arnt C-terminal pas domain, 3 residue ib slip”. Solution nmr, 1 pocket (best druggability 0.38). MolNFT v1 #42086 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2K7S
Type: protein
Length: 119 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Aryl hydrocarbon receptor nuclear translocator
UniProt: P27540
Pockets: 1 · best druggability 0.38

Structure

solution nmr · 1 distinct chain · 26% helix, 32% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Aryl hydrocarbon receptor nuclear translocator	protein	119	26% helix, 32% strand	P27540

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	70	0.38	0.78	17	empty

Compared structures

2K7S · Human ARNT C-Terminal PAS Domain, 3 Residue IB slip · the same entry in another collection · chain A against A, TM-score 1.00
P27540 · AlphaFold monomer V2.0 prediction for aryl hydrocarbon receptor nuclear translocator… · a predicted model of the same protein · chain A against A, TM-score 0.79

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P27540
Elsewhere: RCSB PDB 2K7S · PDBe 2K7S · UniProt P27540

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