MolNFT v1 · #42084 · protein

Filamin a ig-like domains 18-19

2K7Q · Filamin-a: “Filamin a ig-like domains 18-19”. Solution nmr, 1 pocket (best druggability 0.48). MolNFT v1 #42084 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2K7Q
Type: protein
Length: 191 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Filamin-a
UniProt: P21333
Pockets: 1 · best druggability 0.48

Structure

solution nmr · 1 distinct chain · 6% helix, 50% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Filamin-a	protein	191	6% helix, 50% strand	P21333

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	93	0.48	0.81	23	empty

Compared structures

2K7Q · Filamin A Ig-like domains 18-19 · the same entry in another collection · chain A against A, TM-score 1.00
P21333 · AlphaFold monomer V2.0 prediction for filamin-a (P21333) · a predicted model of the same protein · chain A against A, TM-score 0.53

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P21333
Elsewhere: RCSB PDB 2K7Q · PDBe 2K7Q · UniProt P21333

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