MolNFT v1 · #42041 · protein
NMR structure of an unusually 28 kda active mutant of maize ribosome- inactivating protein (mod)
2K6H · Ribosome-inactivating protein: “NMR structure of an unusually 28 kda active mutant of maize ribosome- inactivating protein (mod)”. Solution nmr, 3 pockets (best druggability 0.50). MolNFT v1 #42041 on GenesisL1: 3D structure…
- PDB
- 2K6H
- Type
- protein
- Length
- 248 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ribosome-inactivating protein
- EC
- 3.2.2.22
- UniProt
- P28522
- Pockets
- 3 · best druggability 0.50
Structure
solution nmr · 1 distinct chain · 39% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ribosome-inactivating protein (EC 3.2.2.22) | protein | 248 | 39% helix, 18% strand | P28522 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 160 | 0.50 | 0.78 | 29 | empty |
| 2 | 52 | 0.36 | 0.79 | 12 | empty |
| 3 | 55 | 0.34 | 0.78 | 16 | empty |
Compared structures
- 2K6H · NMR structure of an unusually 28 kDa Active Mutant of Maize Ribosome-Inactivating protein… · the same entry in another collection · chain A against A, TM-score 1.00
- P28522 · AlphaFold monomer V2.0 prediction for ribosome-inactivating protein (P28522) · a predicted model of the same protein · chain A against A, TM-score 0.91
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P28522
- Elsewhere: RCSB PDB 2K6H · PDBe 2K6H · UniProt P28522
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