MolNFT v1 · #41731 · protein

Solution structure of periplasmic domain of tolr from H. influenzae with saxs data

2JWL · Protein tolr: “Solution structure of periplasmic domain of tolr from H. influenzae with saxs data”. Solution nmr, 1 pocket (best druggability 0.46). MolNFT v1 #41731 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2JWL
Type: protein
Length: 148 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein tolr
UniProt: P43769
Pockets: 1 · best druggability 0.46

Structure

solution nmr · 1 distinct chain · 36% helix, 28% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Protein tolr	protein	74	36% helix, 28% strand	P43769

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	196	0.46	0.74	35	empty

Interfaces

1 interface between chains.

A–B · 881 Å² buried · 11 hydrogen bonds · protein-protein

Compared structures

2JWL · Solution Structure of periplasmic domain of TolR from H. influenzae with SAXS data · the same entry in another collection · chain A against A, TM-score 1.00
P43769 · AlphaFold monomer V2.0 prediction for tol-pal system protein tolr (P43769) · a predicted model of the same protein · chain A against A, TM-score 0.90

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P43769
Elsewhere: RCSB PDB 2JWL · PDBe 2JWL · UniProt P43769

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