MolNFT v1 · #41148 · protein

Crystal structure of a trypsin-like mutant (S189D , A226G) chymotrypsin.

2JET · Chymotrypsinogen B chain a: “Crystal structure of a trypsin-like mutant (S189D , A226G) chymotrypsin.”. X-ray diffraction. MolNFT v1 #41148 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2JET
Type: protein
Length: 230 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Chymotrypsinogen B chain a; Chymotrypsinogen B chain B; Chymotrypsinogen B chain C
EC: 3.4.21.1
UniProt: P07338

Structure

x-ray diffraction · 3 distinct chains · 10% helix, 33% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Chymotrypsinogen B chain a (EC 3.4.21.1)	protein	12	0% helix, 0% strand	P07338
B	Chymotrypsinogen B chain B (EC 3.4.21.1)	protein	125	0% helix, 36% strand	P07338
C	Chymotrypsinogen B chain C (EC 3.4.21.1)	protein	93	24% helix, 34% strand	P07338

Interfaces

3 interfaces between chains.

B–C · 2624 Å² buried · 42 hydrogen bonds · protein-protein
A–B · 542 Å² buried · 5 hydrogen bonds · protein-protein
A–C · 261 Å² buried · 2 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 5 disulfide (disulfide).

Compared structures

2JET · Crystal structure of a trypsin-like mutant (S189D , A226G) chymotrypsin. · the same entry in another collection · chain A against A, TM-score 1.00
P07338 · AlphaFold monomer V2.0 prediction for chymotrypsinogen B (P07338) · a predicted model of the same protein · chain B against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P07338
Elsewhere: RCSB PDB 2JET · PDBe 2JET · UniProt P07338

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