Research workbench
Crystal structure of a trypsin-like mutant (S189D , A226G) chymotrypsin.
Analyse Crystal structure of a trypsin-like mutant (S189D , A226G) chymotrypsin. in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2JET
- Type
- protein
- Length
- 230 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Chymotrypsinogen B chain a; Chymotrypsinogen B chain B; Chymotrypsinogen B chain C
- EC
- 3.4.21.1
- UniProt
- P07338
Structure
x-ray diffraction · 3 distinct chains · 10% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Chymotrypsinogen B chain a (EC 3.4.21.1) | protein | 12 | 0% helix, 0% strand | P07338 |
| B | Chymotrypsinogen B chain B (EC 3.4.21.1) | protein | 125 | 0% helix, 36% strand | P07338 |
| C | Chymotrypsinogen B chain C (EC 3.4.21.1) | protein | 93 | 24% helix, 34% strand | P07338 |
Interfaces
3 interfaces between chains.
- B–C · 2624 Ų buried · 42 hydrogen bonds · protein-protein
- A–B · 542 Ų buried · 5 hydrogen bonds · protein-protein
- A–C · 261 Ų buried · 2 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 5 disulfide (disulfide).
Compared structures
- 2JET · Crystal structure of a trypsin-like mutant (S189D , A226G) chymotrypsin. · the same entry in another collection · chain A against A, TM-score 1.00
- P07338 · AlphaFold monomer V2.0 prediction for chymotrypsinogen B (P07338) · a predicted model of the same protein · chain B against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P07338
- Elsewhere: RCSB PDB 2JET · PDBe 2JET · UniProt P07338
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