MolNFT v1 · #41141 · protein

Native family 12 xyloglucanase from bacillus licheniformis

2JEM · Endo-beta-1,4-glucanase: “Native family 12 xyloglucanase from bacillus licheniformis”. X-ray diffraction, 2 pockets (best druggability 0.45). MolNFT v1 #41141 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2JEM
Type: protein
Length: 464 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Endo-beta-1,4-glucanase
EC: 3.2.1.4, 3.2.1.151
UniProt: Q7X4S4
Pockets: 2 · best druggability 0.45

Structure

x-ray diffraction · 1 distinct chain · 6% helix, 55% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Endo-beta-1,4-glucanase (EC 3.2.1.4, 3.2.1.151)	protein	232	6% helix, 55% strand	Q7X4S4

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	133	0.45	0.77	23	empty
2	126	0.44	0.76	23	empty

Interfaces

1 interface between chains.

A–B · 615 Å² buried · 7 hydrogen bonds · protein-protein

Compared structures

2JEM · Native family 12 xyloglucanase from Bacillus licheniformis · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7X4S4
Elsewhere: RCSB PDB 2JEM · PDBe 2JEM · UniProt Q7X4S4

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