MolNFT v1 · #41037 · protein
Phob response regulator receiver domain constitutively- active double mutant D10A and D53E.
2JB9 · Phosphate regulon transcriptional regulatory protein phob: “Phob response regulator receiver domain constitutively- active double mutant D10A and D53E.”. X-ray diffraction, 1 pocket (best druggability 0.64). MolNFT v1 #41037 on…
- PDB
- 2JB9
- Type
- protein
- Length
- 243 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phosphate regulon transcriptional regulatory protein phob
- UniProt
- P0AFJ5
- Pockets
- 1 · best druggability 0.64
Structure
x-ray diffraction · 2 distinct chains · 42% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphate regulon transcriptional regulatory protein phob | protein | 121 | 44% helix, 21% strand | P0AFJ5 |
| B | Phosphate regulon transcriptional regulatory protein phob | protein | 122 | 39% helix, 20% strand | P0AFJ5 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 203 | 0.64 | 0.83 | 19 | empty |
Interfaces
1 interface between chains.
- A–B · 610 Ų buried · 1 hydrogen bond · protein-protein
Compared structures
- 2JB9 · PhoB response regulator receiver domain constitutively-active double mutant D10A and D53E. · the same entry in another collection · chain A against A, TM-score 1.00
- P0AFJ5 · AlphaFold monomer V2.0 prediction for phosphate regulon transcriptional regulatory… · a predicted model of the same protein · chain B against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0AFJ5
- Elsewhere: RCSB PDB 2JB9 · PDBe 2JB9 · UniProt P0AFJ5
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