UniProt P0AFJ5
Phosphate regulon transcriptional regulatory protein phob (P0AFJ5)
Phosphate regulon transcriptional regulatory protein phob (UniProt P0AFJ5): 12 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0AFJ5
- Protein
- Phosphate regulon transcriptional regulatory protein phob
- Experimental structures
- 12
- Predicted models
- 1
- Pockets
- 1 · 1 record with a druggable one
Structures
13 records of P0AFJ5 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1GXQ | Crystal structure of the PhoB effector domain | x-ray diffraction | A | — | — |
| 1GXQ | Crystal structure of the phob effector domain | x-ray diffraction | A | — | — |
| 2IYN | The co-factor-induced pre-active conformation in PhoB | x-ray diffraction | A, B, C | — | — |
| 2IYN | The co-factor-induced pre-active conformation in phob | x-ray diffraction | A, B, C | — | — |
| 2JB9 | PhoB response regulator receiver domain constitutively-active double mutant D10A and D53E. | x-ray diffraction | A, B | — | — |
| 2JB9 | Phob response regulator receiver domain constitutively- active double mutant D10A and D53E. | x-ray diffraction | A, B | — | — |
| 2JBA | PhoB response regulator receiver domain constitutively-active double mutant D53A and Y102C. | x-ray diffraction | A, B | — | — |
| 2JBA | Phob response regulator receiver domain constitutively- active double mutant D53A and Y102C. | x-ray diffraction | A, B | — | — |
| 2Z33 | Solution structure of the DNA complex of PhoB DNA-binding/transactivation Domain | solution nmr | A | — | — |
| 2Z33 | Solution structure of the DNA complex of phob DNA- BINDING/TRANSACTIVATION domain | solution nmr | A | — | — |
| 3T72 | PhoB(E)-Sigma70(4)-(RNAP-Betha-flap-tip-helix)-DNA Transcription Activation Sub-Complex | x-ray diffraction | A, B, E, F, I, J, M, N, R, S, V, W, Z, 1, 4, 5, 8, 9, c, d, g, h, k, l | — | — |
| 3T72 | PHOB(E)-SIGMA70(4)-(rnap-betha-flap-tip-helix)-DNA transcription activation sub-complex | x-ray diffraction | A, B, E, F, I, J, M, N, R, S, V, W, Z, 1, 4, 5, 8, 9, c, d, g, h, k, l | — | — |
| P0AFJ5 | AlphaFold monomer V2.0 prediction for phosphate regulon transcriptional regulatory protein phob… | predicted | A | — | 1 (best 0.60) |
Experiment against prediction
- 2IYN chain C against the predicted model P0AFJ5: TM-score 0.98, RMSD 0.63 Å
- 2IYN chain C against the predicted model P0AFJ5: TM-score 0.98, RMSD 0.63 Å
- 2IYN chain A against the predicted model P0AFJ5: TM-score 0.96, RMSD 0.97 Å
- 2IYN chain A against the predicted model P0AFJ5: TM-score 0.96, RMSD 0.97 Å
- 3T72 chain A against the predicted model P0AFJ5: TM-score 0.95, RMSD 1.10 Å
- 3T72 chain A against the predicted model P0AFJ5: TM-score 0.95, RMSD 1.10 Å
- 1GXQ chain A against the predicted model P0AFJ5: TM-score 0.94, RMSD 1.11 Å
- 1GXQ chain A against the predicted model P0AFJ5: TM-score 0.94, RMSD 1.11 Å
- 2JB9 chain B against the predicted model P0AFJ5: TM-score 0.94, RMSD 1.04 Å
- 2JB9 chain B against the predicted model P0AFJ5: TM-score 0.94, RMSD 1.04 Å
Elsewhere
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