MolNFT v1 · #40001 · protein
Human isopentenyl diphophate isomerase complexed with substrate analog
2ICK · Isopentenyl-diphosphate delta isomerase: “Human isopentenyl diphophate isomerase complexed with substrate analog”. X-ray diffraction, 2 ligands (DMA, MN), 1 pocket (best druggability 0.70). MolNFT v1 #40001 on GenesisL1: 3D…
- PDB
- 2ICK
- Type
- protein
- Length
- 220 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Isopentenyl-diphosphate delta isomerase
- EC
- 5.3.3.2
- UniProt
- Q86U81
- Ligands
- DMA, MN
- Pockets
- 1 · best druggability 0.70
Structure
x-ray diffraction · 1 distinct chain · 31% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Isopentenyl-diphosphate delta isomerase (EC 5.3.3.2) | protein | 220 | 31% helix, 31% strand | Q86U81 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 60 | 0.70 | 0.97 | 24 | DMA |
Compared structures
- 2ICK · Human isopentenyl diphophate isomerase complexed with substrate analog · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q86U81
- Elsewhere: RCSB PDB 2ICK · PDBe 2ICK · UniProt Q86U81
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.