MolNFT v1 · #39702 · protein
Crystal structure analysis of the nurse shark new antigen receptor ancestral variable domain
2I27: “Crystal structure analysis of the nurse shark new antigen receptor ancestral variable domain”. X-ray diffraction, 1 pocket (best druggability 0.38). MolNFT v1 #39702 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2I27
- Type
- protein
- Length
- 217 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- New antigen receptor ancestral
- UniProt
- Q8JGJ1
- Pockets
- 1 · best druggability 0.38
Structure
x-ray diffraction · 2 distinct chains · 6% helix, 50% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| N | New antigen receptor ancestral | protein | 109 | 6% helix, 50% strand | Q8JGJ1 |
| O | New antigen receptor ancestral | protein | 108 | 6% helix, 50% strand | Q8JGJ1 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 115 | 0.38 | 0.75 | 29 | empty |
Interfaces
1 interface between chains.
- N–O · 541 Ų buried · 13 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 3 disulfide (disulfide).
Compared structures
- 2I27 · Crystal Structure Analysis of the Nurse Shark New Antigen Receptor Ancestral variable… · the same entry in another collection · chain N against N, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8JGJ1
- Elsewhere: RCSB PDB 2I27 · PDBe 2I27 · UniProt Q8JGJ1
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