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MolNFT v1 · #39468 · protein

X-ray crystal structure of the GRB2 SH2 domain complexed to a constrained and cyclopropane-derived ligand

2HUW: “X-ray crystal structure of the GRB2 SH2 domain complexed to a constrained and cyclopropane-derived ligand”. X-ray diffraction. MolNFT v1 #39468 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
2HUW
Type
protein
Length
199 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P62993

Structure

x-ray diffraction · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein101—P62993
B—protein98—P62993

Compared structures

  • 2HUW · X-ray crystal structure of the Grb2 SH2 domain complexed to a constrained and… · the same entry in another collection · chain A against A, TM-score 1.00
  • P62993 · AlphaFold monomer V2.0 prediction for growth factor receptor-bound protein 2 (P62993) · a predicted model of the same protein · chain B against A, TM-score 0.97

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