MolNFT v1 · #39240 · protein
Structure of human FE65-ww domain in complex with hmena peptide.
2HO2 · Amyloid beta A4 protein-binding family B member 1: “Structure of human FE65-ww domain in complex with hmena peptide.”. X-ray diffraction. MolNFT v1 #39240 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2HO2
- Type
- protein
- Length
- 43 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Amyloid beta A4 protein-binding family B member 1; Protein enabled homolog
- UniProt
- O00213, Q8N8S7
Structure
x-ray diffraction · 2 distinct chains · 0% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Amyloid beta A4 protein-binding family B member 1 | protein | 33 | 0% helix, 39% strand | O00213 |
| B | Protein enabled homolog | protein | 10 | 0% helix, 0% strand | Q8N8S7 |
Ligands and binding sites
- GOL · Glycerol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 282 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 2HO2 · Structure of human FE65-WW domain in complex with hMena peptide. · the same entry in another collection · chain A against A, TM-score 1.00
- O00213 · AlphaFold monomer V2.0 prediction for amyloid-beta A4 precursor protein-binding family B… · a predicted model of the same protein · chain A against A, TM-score 0.83
- Q8N8S7 · AlphaFold monomer V2.0 prediction for protein enabled homolog (Q8N8S7) · a predicted model of the same protein · chain B against A, TM-score 0.55
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O00213
- Every structure of UniProt Q8N8S7
- Elsewhere: RCSB PDB 2HO2 · PDBe 2HO2 · UniProt O00213 · UniProt Q8N8S7
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.