MolNFT v1 · #38358 · protein
Crystal structure of plasmodium vivax orotidine 5-monophosphate decarboxylase with 6-aza-ump bound
2GUU · Odcase: “Crystal structure of plasmodium vivax orotidine 5-monophosphate decarboxylase with 6-aza-ump bound”. X-ray diffraction, 1 ligand (UP6), 2 pockets (best druggability 0.50). MolNFT v1 #38358 on GenesisL1: 3D structure…
- PDB
- 2GUU
- Type
- protein
- Length
- 317 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Odcase
- Ligands
- UP6
- Pockets
- 2 · best druggability 0.50
Structure
x-ray diffraction · 1 distinct chain · 52% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Odcase | protein | 317 | 52% helix, 15% strand | — |
Ligands and binding sites
- UP6 · 6-aza uridine 5'-monophosphate · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 122 | 0.50 | 0.81 | 27 | UP6 |
| 2 | 108 | 0.38 | 0.74 | 17 | empty |
Compared structures
- 2GUU · crystal structure of Plasmodium vivax orotidine 5-monophosphate decarboxylase with… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 2GUU · PDBe 2GUU
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