MolNFT v1 · #37958 · protein
Crystal structure of SARS spike protein receptor binding domain
2GHV · Spike glycoprotein: “Crystal structure of SARS spike protein receptor binding domain”. X-ray diffraction, 1 pocket (best druggability 0.28). MolNFT v1 #37958 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2GHV
- Type
- protein
- Length
- 366 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Spike glycoprotein
- UniProt
- P59594
- Pockets
- 1 · best druggability 0.28
Structure
x-ray diffraction · 1 distinct chain · 20% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| E, C | Spike glycoprotein | protein | 183 | 20% helix, 28% strand | P59594 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 59 | 0.28 | 0.74 | 14 | empty |
Interfaces
1 interface between chains.
- E–C · 1032 Ų buried · 6 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 disulfide (disulfide).
Compared structures
- 2GHV · Crystal structure of SARS spike protein receptor binding domain · the same entry in another collection · chain E against E, TM-score 1.00
- 3SCJ · Crystal structure of spike protein receptor-binding domain from a predicted SARS… · a predicted model of the same protein · chain E against E, TM-score 0.87
- 3SCI · Crystal structure of spike protein receptor-binding domain from a predicted SARS… · a predicted model of the same protein · chain E against E, TM-score 0.87
- 3SCK · Crystal structure of spike protein receptor-binding domain from a predicted SARS… · a predicted model of the same protein · chain E against E, TM-score 0.87
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P59594
- Elsewhere: RCSB PDB 2GHV · PDBe 2GHV · UniProt P59594
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.