MolNFT v1 · #37868 · protein

Structure of intact fadd (MORT1)

2GF5 · Fadd protein: “Structure of intact fadd (MORT1)”. Solution nmr, 1 pocket (best druggability 0.67). MolNFT v1 #37868 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2GF5
Type: protein
Length: 191 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Fadd protein
UniProt: Q13158
Pockets: 1 · best druggability 0.67

Structure

solution nmr · 1 distinct chain · 69% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Fadd protein	protein	191	69% helix, 0% strand	Q13158

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	307	0.67	0.82	39	empty

Compared structures

2GF5 · Structure of intact FADD (MORT1) · the same entry in another collection · chain A against A, TM-score 1.00
Q13158 · AlphaFold monomer V2.0 prediction for fas-associated death domain protein (Q13158) · a predicted model of the same protein · chain A against A, TM-score 0.48

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q13158
Elsewhere: RCSB PDB 2GF5 · PDBe 2GF5 · UniProt Q13158

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