UniProt Q13158
FAS-associated death domain protein (Q13158)
FAS-associated death domain protein (UniProt Q13158): 16 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q13158
- Protein
- FAS-associated death domain protein
- Experimental structures
- 16
- Predicted models
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
17 records of Q13158 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1A1W | Fadd death effector domain, F25Y mutant, NMR minimized average structure | solution nmr | A | — | — |
| 1A1W | Fadd death effector domain, F25Y mutant, NMR minimized average structure | solution nmr | A | — | — |
| 1A1Z | Fadd death effector domain, F25G mutant, NMR minimized average structure | solution nmr | A | — | — |
| 1A1Z | Fadd death effector domain, F25G mutant, NMR minimized average structure | solution nmr | A | — | — |
| 1E3Y | Death domain from human FADD/MORT1 | solution nmr | A | — | — |
| 1E3Y | Death domain from human FADD/MORT1 | solution nmr | A | — | — |
| 1E41 | Death domain from human FADD/MORT1 | solution nmr | A | — | — |
| 1E41 | Death domain from human FADD/MORT1 | solution nmr | A | — | — |
| 2GF5 | Structure of intact FADD (MORT1) | solution nmr | A | — | — |
| 2GF5 | Structure of intact fadd (MORT1) | solution nmr | A | — | — |
| 3EZQ | Crystal Structure of the Fas/FADD Death Domain Complex | x-ray diffraction | B, D, F, H, J, L, N, P | — | — |
| 3EZQ | Crystal structure of the FAS/FADD death domain complex | x-ray diffraction | B, D, F, H, J, L, N, P | — | — |
| 3OQ9 | Structure of the FAS/FADD death domain assembly | x-ray diffraction | H, I, J, K, L | — | — |
| 3OQ9 | Structure of the FAS/FADD death domain assembly | x-ray diffraction | H, I, J, K, L | — | — |
| 6ACI | Crystal structure of epec effector nleb in complex with fadd death domain | x-ray diffraction | H | — | — |
| 8YD8 | Structure of FADD/Caspase-8/cFLIP death effector domain assembly | x-ray diffraction | L | — | 5 (best 0.73) |
| Q13158 | AlphaFold monomer V2.0 prediction for fas-associated death domain protein (Q13158) | predicted | A | — | — |
Experiment against prediction
- 3OQ9 chain I against the predicted model Q13158: TM-score 0.95, RMSD 0.80 Å
- 3OQ9 chain I against the predicted model Q13158: TM-score 0.95, RMSD 0.80 Å
- 3OQ9 chain H against the predicted model Q13158: TM-score 0.95, RMSD 0.80 Å
- 3OQ9 chain H against the predicted model Q13158: TM-score 0.95, RMSD 0.80 Å
- 3OQ9 chain L against the predicted model Q13158: TM-score 0.95, RMSD 0.80 Å
- 3OQ9 chain L against the predicted model Q13158: TM-score 0.95, RMSD 0.80 Å
- 3OQ9 chain J against the predicted model Q13158: TM-score 0.95, RMSD 0.80 Å
- 3OQ9 chain J against the predicted model Q13158: TM-score 0.95, RMSD 0.80 Å
- 3OQ9 chain K against the predicted model Q13158: TM-score 0.95, RMSD 0.80 Å
- 3OQ9 chain K against the predicted model Q13158: TM-score 0.95, RMSD 0.80 Å
Elsewhere
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