MolNFT v1 · #37655 · protein
Structurally mapping the diverse phenotype of adeno- associated virus serotype 4
2G8G · Capsid: “Structurally mapping the diverse phenotype of adeno- associated virus serotype 4”. X-ray diffraction, 1 ligand (D5M), 7 pockets (best druggability 0.62). MolNFT v1 #37655 on GenesisL1: 3D structure, binding sites and…
- PDB
- 2G8G
- Type
- protein
- Length
- 524 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Capsid
- UniProt
- O41855
- Ligands
- D5M
- Pockets
- 7 · best druggability 0.62
Structure
x-ray diffraction · 1 distinct chain · 6% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Capsid | protein | 524 | 6% helix, 33% strand | O41855 |
Ligands and binding sites
- D5M · 2'-deoxyadenosine-5'-monophosphate · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 508 | 0.62 | 0.75 | 63 | empty |
| 2 | 225 | 0.51 | 0.75 | 34 | empty |
| 3 | 199 | 0.47 | 0.75 | 30 | empty |
| 4 | 97 | 0.41 | 0.77 | 19 | D5M |
| 5 | 62 | 0.32 | 0.76 | 21 | empty |
Compared structures
- 2G8G · Structurally mapping the diverse phenotype of Adeno-Associated Virus serotype 4 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O41855
- Elsewhere: RCSB PDB 2G8G · PDBe 2G8G · UniProt O41855
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