MolNFT v1 · #37588 · protein
Crystal structure of human RAB26 in complex with a GTP analogue
2G6B · RAS-related protein rab-26: “Crystal structure of human RAB26 in complex with a GTP analogue”. X-ray diffraction, 3 ligands (GNP, MG, UNX), 1 pocket (best druggability 0.54). MolNFT v1 #37588 on GenesisL1: 3D structure, binding…
- PDB
- 2G6B
- Type
- protein
- Length
- 162 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RAS-related protein rab-26
- UniProt
- Q9ULW5
- Ligands
- GNP, MG, UNX
- Pockets
- 1 · best druggability 0.54
Structure
x-ray diffraction · 1 distinct chain · 33% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RAS-related protein rab-26 | protein | 162 | 33% helix, 27% strand | Q9ULW5 |
Ligands and binding sites
- GNP · Phosphoaminophosphonic acid-guanylate ester · ligand · chains A
- MG · Magnesium ion · metal · chains A
- UNX · Unknown atom or ion · ion · 4 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 142 | 0.54 | 0.81 | 28 | MG, GNP |
Compared structures
- 2G6B · Crystal structure of human RAB26 in complex with a GTP analogue · the same entry in another collection · chain A against A, TM-score 1.00
- Q9ULW5 · AlphaFold monomer V2.0 prediction for RAS-related protein rab-26 (Q9ULW5) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9ULW5
- Elsewhere: RCSB PDB 2G6B · PDBe 2G6B · UniProt Q9ULW5
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.