MolNFT v1 · #37386 · protein
Structure of the E. COLI puta proline dehydrogenase domain reduced by dithionite and complexed with SO2
2FZM · Bifunctional protein puta, proline dehydrogenase (ec…: “Structure of the E. COLI puta proline dehydrogenase domain reduced by dithionite and complexed with SO2”. X-ray diffraction, 2 ligands (FAD, SO2), 3 pockets (best druggability…
- PDB
- 2FZM
- Type
- protein
- Length
- 450 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Bifunctional protein puta, proline dehydrogenase (ec 1.5.99.8) (proline oxidase)
- EC
- 1.5.99.8
- UniProt
- P09546
- Ligands
- FAD, SO2
- Pockets
- 3 · best druggability 0.84
Structure
x-ray diffraction · 1 distinct chain · 56% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Bifunctional protein puta, proline dehydrogenase (ec 1.5.99.8) (proline oxidase) (EC 1.5.99.8) | protein | 450 | 56% helix, 10% strand | P09546 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 473 | 0.84 | 0.91 | 43 | FAD, SO2 |
| 2 | 173 | 0.52 | 0.78 | 25 | empty |
| 3 | 63 | 0.33 | 0.76 | 14 | empty |
Compared structures
- 2FZM · Structure of the E. coli PutA proline dehydrogenase domain reduced by dithionite and… · the same entry in another collection · chain A against A, TM-score 1.00
- P09546 · AlphaFold monomer V2.0 prediction for bifunctional protein puta (P09546) · a predicted model of the same protein · chain A against A, TM-score 0.91
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P09546
- Elsewhere: RCSB PDB 2FZM · PDBe 2FZM · UniProt P09546
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