MolNFT v1 · #37272 · protein
Structure of pure (N5-carboxyaminoimidazole ribonucleotide mutase) from the acidophilic bacterium acetobacter aceti, at pH 8.5
2FW1: “Structure of pure (N5-carboxyaminoimidazole ribonucleotide mutase) from the acidophilic bacterium acetobacter…”. X-ray diffraction, 2 pockets (best druggability 0.32). MolNFT v1 #37272 on GenesisL1: 3D structure, binding sites and…
- PDB
- 2FW1
- Type
- protein
- Length
- 320 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- N5-carboxyaminoimidazole ribonucleotide mutase
- UniProt
- Q2QJL3
- Pockets
- 2 · best druggability 0.32
Structure
x-ray diffraction · 2 distinct chains · 48% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | N5-carboxyaminoimidazole ribonucleotide mutase | protein | 159 | 48% helix, 16% strand | Q2QJL3 |
| B | N5-carboxyaminoimidazole ribonucleotide mutase | protein | 161 | 47% helix, 16% strand | Q2QJL3 |
Ligands and binding sites
- ACY · Acetic acid · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 65 | 0.32 | 0.76 | 17 | empty |
| 2 | 54 | 0.29 | 0.75 | 14 | empty |
Interfaces
1 interface between chains.
- A–B · 1651 Ų buried · 29 hydrogen bonds · protein-protein
Compared structures
- 2FW1 · Structure of PurE (N5-carboxyaminoimidazole ribonucleotide mutase) from the acidophilic… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q2QJL3
- Elsewhere: RCSB PDB 2FW1 · PDBe 2FW1 · UniProt Q2QJL3
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