MolNFT v1 · #36515 · protein

Hmg-CoA synthase from brassica juncea in the apo-form

2F82: “Hmg-CoA synthase from brassica juncea in the apo-form”. X-ray diffraction, 3 pockets (best druggability 0.75). MolNFT v1 #36515 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2F82
Type: protein
Length: 450 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Hmg-CoA synthase
UniProt: Q9M6U3
Pockets: 3 · best druggability 0.75

Structure

x-ray diffraction · 1 distinct chain · 43% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Hmg-CoA synthase	protein	450	43% helix, 22% strand	Q9M6U3

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	517	0.75	0.83	59	empty
2	260	0.65	0.82	26	empty
3	146	0.50	0.79	28	empty

Compared structures

2F82 · HMG-CoA synthase from Brassica juncea in the apo-form · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9M6U3
Elsewhere: RCSB PDB 2F82 · PDBe 2F82 · UniProt Q9M6U3

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