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UniProt Q9M6U3

3-hydroxy-3-methylglutaryl coenzyme A synthase (Q9M6U3)

3-hydroxy-3-methylglutaryl coenzyme A synthase (UniProt Q9M6U3), EC 2.3.3.10: 10 experimental structures on GenesisL1, 3 ligands bound, 22 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q9M6U3
Protein
3-hydroxy-3-methylglutaryl coenzyme A synthase
EC
2.3.3.10
Experimental structures
10
Predicted models
0
Ligands
3
Pockets
22 · 2 records with a druggable one

Structures

10 records of Q9M6U3 in the MolNFT archive: 10 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
2F82HMG-CoA synthase from Brassica juncea in the apo-formx-ray diffractionA——
2F82Hmg-CoA synthase from brassica juncea in the apo-formx-ray diffractionA——
2F9AHMG-CoA synthase from Brassica juncea in complex with F-244x-ray diffractionAF242 (best 0.77)
2F9AHmg-CoA synthase from brassica juncea in complex with F-244x-ray diffractionA——
2FA0HMG-CoA synthase from Brassica juncea in complex with HMG-CoA and covalently bound to HMG-CoAx-ray diffractionA——
2FA0Hmg-CoA synthase from brassica juncea in complex with hmg-CoA and covalently bound to hmg-CoAx-ray diffractionA——
2FA3HMG-CoA synthase from Brassica juncea in complex with acetyl-CoA and acetyl-cys117.x-ray diffractionA——
2FA3Hmg-CoA synthase from brassica juncea in complex with acetyl-CoA and acetyl-CYS117.x-ray diffractionA——
7CQTCrystal structure of Brassica juncea HMG-CoA synthase 1 mutant - S359A in complex with acetyl-CoAx-ray diffractionA, B, C, DACO, A3P20 (best 0.83)
7CQTCrystal structure of brassica juncea hmg-CoA synthase 1 mutant - S359A in complex with acetyl-CoAx-ray diffractionA, B, C, DACO, A3P—

Ligands

  • A3P · Adenosine-3'-5'-diphosphate · in 2 records
  • ACO · Acetyl coenzyme *A · in 2 records
  • F24 · (7R,12R,13R)-13-formyl-12,14-dihydroxy-3,5,7-trimethyltetradeca-2,4-dienoic acid · in 1 record

Elsewhere

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