MolNFT v1 · #36493 · protein
Catm effector binding domain with its effector CIS,CIS-muconate
2F7C · Hth-type transcriptional regulator catm: “Catm effector binding domain with its effector CIS,CIS-muconate”. X-ray diffraction, 2 ligands (CCU, SO4), 2 pockets (best druggability 0.62). MolNFT v1 #36493 on GenesisL1: 3D structure…
- PDB
- 2F7C
- Type
- protein
- Length
- 216 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Hth-type transcriptional regulator catm
- UniProt
- P07774
- Ligands
- CCU, SO4
- Pockets
- 2 · best druggability 0.62
Structure
x-ray diffraction · 1 distinct chain · 32% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Hth-type transcriptional regulator catm | protein | 216 | 32% helix, 29% strand | P07774 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 121 | 0.62 | 0.87 | 25 | CCU |
| 2 | 75 | 0.53 | 0.85 | 18 | empty |
Compared structures
- 2F7C · CatM effector binding domain with its effector cis,cis-muconate · the same entry in another collection · chain A against A, TM-score 1.00
- P07774 · AlphaFold monomer V2.0 prediction for hth-type transcriptional regulator catm (P07774) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P07774
- Elsewhere: RCSB PDB 2F7C · PDBe 2F7C · UniProt P07774
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