MolNFT v1 · #36443 · protein

Structural characterization of the UL25 DNA packaging protein from herpes simplex virus type 1

2F5U · Virion protein UL25: “Structural characterization of the UL25 DNA packaging protein from herpes simplex virus type 1”. X-ray diffraction, 8 pockets (best druggability 0.57). MolNFT v1 #36443 on GenesisL1: 3D structure, binding sites…

PDB: 2F5U
Type: protein
Length: 410 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Virion protein UL25
UniProt: P10209
Pockets: 8 · best druggability 0.57

Structure

x-ray diffraction · 1 distinct chain · 55% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Virion protein UL25	protein	410	55% helix, 2% strand	P10209

Pockets

8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	171	0.57	0.81	34	empty
2	101	0.51	0.82	20	empty
3	106	0.50	0.81	17	empty
4	145	0.48	0.78	40	empty
5	90	0.44	0.80	18	empty

Compared structures

2F5U · Structural Characterization of the UL25 DNA Packaging Protein from Herpes Simplex Virus… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P10209
Elsewhere: RCSB PDB 2F5U · PDBe 2F5U · UniProt P10209

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.