MolNFT v1 · #36278 · protein

Crystal structure of staphylococcal nuclease mutant V66L/V99I

2F0T: “Crystal structure of staphylococcal nuclease mutant V66L/V99I”. X-ray diffraction, 1 pocket (best druggability 0.45). MolNFT v1 #36278 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2F0T
Type: protein
Length: 135 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Staphylococcal nuclease
EC: 3.1.31.1
UniProt: P00644
Pockets: 1 · best druggability 0.45

Structure

x-ray diffraction · 1 distinct chain · 27% helix, 33% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Staphylococcal nuclease (EC 3.1.31.1)	protein	135	27% helix, 33% strand	P00644

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	123	0.45	0.78	16	empty

Compared structures

2F0T · Crystal structure of Staphylococcal nuclease mutant V66L/V99I · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P00644
Elsewhere: RCSB PDB 2F0T · PDBe 2F0T · UniProt P00644

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