MolNFT v1 · #36273 · protein

Crystal structure of staphylococcal nuclease mutant V66I/I72V

2F0O: “Crystal structure of staphylococcal nuclease mutant V66I/I72V”. X-ray diffraction, 1 pocket (best druggability 0.48). MolNFT v1 #36273 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2F0O
Type: protein
Length: 136 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Staphylococcal nuclease
EC: 3.1.31.1
UniProt: P00644
Pockets: 1 · best druggability 0.48

Structure

x-ray diffraction · 1 distinct chain · 27% helix, 32% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Staphylococcal nuclease (EC 3.1.31.1)	protein	136	27% helix, 32% strand	P00644

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	152	0.48	0.77	23	empty

Compared structures

2F0O · Crystal structure of Staphylococcal nuclease mutant V66I/I72V · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P00644
Elsewhere: RCSB PDB 2F0O · PDBe 2F0O · UniProt P00644

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