MolNFT v1 · #36008 · protein + RNA

Structure of the SAM domain of VTS1P in complex with RNA

2ESE · 5'-R(*GP*GP*AP*GP*AP*GP*GP*CP*UP*CP*UP*GP*GP*CP*AP*GP*CP*UP…: “Structure of the SAM domain of VTS1P in complex with RNA”. Solution nmr, 1 pocket (best druggability 0.50). MolNFT v1 #36008 on GenesisL1: 3D structure, binding sites…

PDB: 2ESE
Type: protein + RNA
Length: 104 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 5'-R(*GP*GP*AP*GP*AP*GP*GP*CP*UP*CP*UP*GP*GP*CP*AP*GP*CP*UP *UP*UP*UP*CP*C)-3'; VTS1P
Pockets: 1 · best druggability 0.50

Structure

solution nmr · 2 distinct chains · 57% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
B	5'-R(GPGPAPGPAPGPGPCPUPCPUPGPGPCPAPGPCPUP UPUPUPCP*C)-3'	rna	23	—	—
A	VTS1P	protein	81	57% helix, 0% strand	—

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	261	0.50	0.75	20	empty

Interfaces

1 interface between chains.

B–A · 532 Å² buried · 18 hydrogen bonds · protein-nucleic

Compared structures

2ESE · Structure of the SAM domain of Vts1p in complex with RNA · the same entry in another collection · chain B against B, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 2ESE · PDBe 2ESE

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.