MolNFT v1 · #35848 · protein

Solution structure of the C2 domain from human protein kinase C theta

2ENJ · Protein kinase C theta type: “Solution structure of the C2 domain from human protein kinase C theta”. Solution nmr, 1 pocket (best druggability 0.27). MolNFT v1 #35848 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2ENJ
Type: protein
Length: 138 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein kinase C theta type
EC: 2.7.11.13
UniProt: Q04759
Pockets: 1 · best druggability 0.27

Structure

solution nmr · 1 distinct chain · 7% helix, 46% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein kinase C theta type (EC 2.7.11.13)	protein	138	7% helix, 46% strand	Q04759

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	51	0.27	0.74	18	empty

Compared structures

2ENJ · Solution structure of the C2 domain from human protein kinase C theta · the same entry in another collection · chain A against A, TM-score 1.00
Q04759 · AlphaFold monomer V2.0 prediction for protein kinase C theta type (Q04759) · a predicted model of the same protein · chain A against A, TM-score 0.76

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q04759
Elsewhere: RCSB PDB 2ENJ · PDBe 2ENJ · UniProt Q04759

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.