UniProt Q04759
Q04759
Q04759 (UniProt Q04759): 16 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q04759
- Experimental structures
- 16
- Predicted models
- 1
- Ligands
- 1
Structures
17 records of Q04759 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1XJD | Crystal Structure of PKC-theta complexed with Staurosporine at 2A resolution | x-ray diffraction | A | — | — |
| 1XJD | Crystal structure of PKC-theta complexed with staurosporine at 2A resolution | x-ray diffraction | A | — | — |
| 2ENJ | Solution structure of the C2 domain from human protein kinase C theta | solution nmr | A | — | — |
| 2ENJ | Solution structure of the C2 domain from human protein kinase C theta | solution nmr | A | — | — |
| 2ENN | Solution structure of the first C1 domain from human protein kinase C theta | solution nmr | A | — | — |
| 2ENN | Solution structure of the first C1 domain from human protein kinase C theta | solution nmr | A | — | — |
| 2ENZ | Solution structure of the second C1 domain from human protein kinase C theta | solution nmr | A | — | — |
| 2ENZ | Solution structure of the second C1 domain from human protein kinase C theta | solution nmr | A | — | — |
| 2JED | The crystal structure of the kinase domain of the protein kinase C theta in complex with NVP-XAA228… | x-ray diffraction | A, B | — | — |
| 2JED | The crystal structure of the kinase domain of the protein kinase C theta in complex with nvp-XAA228… | x-ray diffraction | A, B | — | — |
| 4Q9Z | Human Protein Kinase C Theta in Complex with Compound35… | x-ray diffraction | A, B | — | — |
| 4Q9Z | Human protein kinase C theta in complex with COMPOUND35 ((1R)-9… | x-ray diffraction | A, B | — | — |
| 4RA5 | Human Protein Kinase C THETA IN COMPLEX WITH LIGAND COMPOUND 11a… | x-ray diffraction | A, B | — | — |
| 4RA5 | Human protein kinase C theta in complex with ligand compound 11A (6… | x-ray diffraction | A, B | — | — |
| 5F9E | Structure of Protein Kinase C theta with compound 10… | x-ray diffraction | A, B | 5VS | — |
| 5F9E | Structure of protein kinase C theta with compound 10: 2,2-dimethyl-7… | x-ray diffraction | A, B | — | — |
| Q04759 | AlphaFold monomer V2.0 prediction for protein kinase C theta type (Q04759) | predicted | A | — | — |
Ligands
- 5VS · 2,2-dimethyl-7-(2-oxidanylidene-3~{H}-imidazo[4,5-b]pyridin-1-yl)-1-(phenylmethyl)-3~{H}-quinazolin-4-one · in 1 record
Experiment against prediction
- 4Q9Z chain A against the predicted model Q04759: TM-score 0.99, RMSD 0.71 Å
- 4Q9Z chain A against the predicted model Q04759: TM-score 0.99, RMSD 0.71 Å
- 4RA5 chain A against the predicted model Q04759: TM-score 0.99, RMSD 0.73 Å
- 4RA5 chain A against the predicted model Q04759: TM-score 0.99, RMSD 0.73 Å
- 2JED chain A against the predicted model Q04759: TM-score 0.98, RMSD 0.90 Å
- 2JED chain A against the predicted model Q04759: TM-score 0.98, RMSD 0.90 Å
- 5F9E chain B against the predicted model Q04759: TM-score 0.98, RMSD 0.91 Å
- 5F9E chain B against the predicted model Q04759: TM-score 0.98, RMSD 0.91 Å
- 1XJD chain A against the predicted model Q04759: TM-score 0.98, RMSD 0.92 Å
- 1XJD chain A against the predicted model Q04759: TM-score 0.98, RMSD 0.92 Å
Elsewhere
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