MolNFT v1 · #35235 · protein

Solution structure of variable-type domain of human receptor for advanced glycation endproducts

2E5E · Advanced glycosylation end product-specific receptor: “Solution structure of variable-type domain of human receptor for advanced glycation endproducts”. Solution nmr, 2 pockets (best druggability 0.68). MolNFT v1 #35235 on…

PDB: 2E5E
Type: protein
Length: 101 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Advanced glycosylation end product-specific receptor
UniProt: Q15109
Pockets: 2 · best druggability 0.68

Structure

solution nmr · 1 distinct chain · 4% helix, 40% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Advanced glycosylation end product-specific receptor	protein	101	4% helix, 40% strand	Q15109

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	84	0.68	0.92	17	empty
2	181	0.53	0.78	32	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

2E5E · Solution Structure of Variable-type Domain of Human Receptor for Advanced Glycation… · the same entry in another collection · chain A against A, TM-score 1.00
Q15109 · AlphaFold monomer V2.0 prediction for advanced glycosylation end product-specific… · a predicted model of the same protein · chain A against A, TM-score 0.68

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q15109
Elsewhere: RCSB PDB 2E5E · PDBe 2E5E · UniProt Q15109

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