MolNFT v1 · #35126 · protein
Crystal structure of a mutant (R612A) of xanthan lyase
2E24: “Crystal structure of a mutant (R612A) of xanthan lyase”. X-ray diffraction, 4 pockets (best druggability 0.76). MolNFT v1 #35126 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2E24
- Type
- protein
- Length
- 752 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Xanthan lyase
- EC
- 4.2.2.12
- UniProt
- Q9AQS0
- Pockets
- 4 · best druggability 0.76
Structure
x-ray diffraction · 1 distinct chain · 32% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Xanthan lyase (EC 4.2.2.12) | protein | 752 | 32% helix, 28% strand | Q9AQS0 |
Ligands and binding sites
- PEG · Di(hydroxyethyl)ether · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1157 | 0.76 | 0.79 | 77 | PEG |
| 2 | 58 | 0.51 | 0.87 | 21 | empty |
| 3 | 138 | 0.41 | 0.75 | 30 | empty |
| 4 | 110 | 0.38 | 0.75 | 18 | empty |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9AQS0
- Elsewhere: RCSB PDB 2E24 · PDBe 2E24 · UniProt Q9AQS0
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