MolNFT v1 · #34556 · protein

Solution structure of SMURF2 WW3 domain-SMAD7 py peptide complex

2DJY · Smad ubiquitination regulatory factor 2: “Solution structure of SMURF2 WW3 domain-SMAD7 py peptide complex”. Solution nmr. MolNFT v1 #34556 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2DJY
Type: protein
Length: 62 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Smad ubiquitination regulatory factor 2; Mothers against decapentaplegic homolog 7
EC: 6.3.2.-
UniProt: Q9HAU4, O15105

Structure

solution nmr · 2 distinct chains · 0% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-)	protein	42	0% helix, 31% strand	Q9HAU4
B	Mothers against decapentaplegic homolog 7	protein	20	0% helix, 0% strand	O15105

Interfaces

1 interface between chains.

A–B · 561 Å² buried · 8 hydrogen bonds · protein-protein

Compared structures

2DJY · Solution structure of Smurf2 WW3 domain-Smad7 PY peptide complex · the same entry in another collection · chain A against A, TM-score 1.00
Q9HAU4 · AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase SMURF2 (Q9HAU4) · a predicted model of the same protein · chain A against A, TM-score 0.78
O15105 · AlphaFold monomer V2.0 prediction for mothers against decapentaplegic homolog 7 (O15105) · a predicted model of the same protein · chain B against A, TM-score 0.16

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9HAU4
Every structure of UniProt O15105
Elsewhere: RCSB PDB 2DJY · PDBe 2DJY · UniProt Q9HAU4 · UniProt O15105

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