MolNFT v1 · #34200 · protein

Solution structure of the third PDZ domain of PDZ domain containing protein 1

2D90: “Solution structure of the third PDZ domain of PDZ domain containing protein 1”. Solution nmr, 1 pocket (best druggability 0.32). MolNFT v1 #34200 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2D90
Type: protein
Length: 102 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: PDZ domain containing protein 1
UniProt: Q9JIL4
Pockets: 1 · best druggability 0.32

Structure

solution nmr · 1 distinct chain · 10% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	PDZ domain containing protein 1	protein	102	10% helix, 25% strand	Q9JIL4

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	71	0.32	0.74	12	empty

Compared structures

2D90 · Solution structure of the third PDZ domain of PDZ domain containing protein 1 · the same entry in another collection · chain A against A, TM-score 1.00
Q9JIL4 · AlphaFold monomer V2.0 prediction for NA(+)/H(+) exchange regulatory cofactor nhe-RF3… · a predicted model of the same protein · chain A against A, TM-score 0.78

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9JIL4
Elsewhere: RCSB PDB 2D90 · PDBe 2D90 · UniProt Q9JIL4

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