MolNFT v1 · #33981 · protein
Structure of human ATG4B
2D1I · Cysteine protease APG4B: “Structure of human ATG4B”. X-ray diffraction, 6 pockets (best druggability 0.62). MolNFT v1 #33981 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2D1I
- Type
- protein
- Length
- 678 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cysteine protease APG4B
- EC
- 3.4.22.-
- UniProt
- Q9Y4P1
- Pockets
- 6 · best druggability 0.62
Structure
x-ray diffraction · 1 distinct chain · 29% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Cysteine protease APG4B (EC 3.4.22.-) | protein | 339 | 29% helix, 19% strand | Q9Y4P1 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 94 | 0.62 | 0.88 | 21 | empty |
| 2 | 58 | 0.55 | 0.89 | 17 | empty |
| 3 | 126 | 0.42 | 0.76 | 18 | empty |
| 4 | 153 | 0.41 | 0.74 | 25 | empty |
| 5 | 97 | 0.34 | 0.73 | 19 | empty |
Interfaces
1 interface between chains.
- A–B · 574 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y4P1
- Elsewhere: RCSB PDB 2D1I · PDBe 2D1I · UniProt Q9Y4P1
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.