MolNFT v1 · #33896 · protein

The crystal structure of canavalia maritima lectin (conm) in complex with trehalose and maltose

2CYF: “The crystal structure of canavalia maritima lectin (conm) in complex with trehalose and maltose”. X-ray diffraction, 3 ligands (GLC, CA, MN), 1 pocket (best druggability 0.30). MolNFT v1 #33896 on GenesisL1: 3D structure, binding…

PDB: 2CYF
Type: protein
Length: 461 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Lectin
Ligands: GLC, CA, MN
Pockets: 1 · best druggability 0.30

Structure

x-ray diffraction · 2 distinct chains · 4% helix, 44% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Lectin	protein	230	4% helix, 43% strand	—
C	Lectin	protein	231	4% helix, 45% strand	—

Ligands and binding sites

GLC · alpha-D-glucopyranose · sugar · 4 copies · chains A, C
CA · Calcium ion · metal · 2 copies · chains A, C
MN · Manganese (II) ion · metal · 2 copies · chains A, C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	58	0.30	0.76	13	empty

Interfaces

1 interface between chains.

A–C · 1007 Å² buried · 22 hydrogen bonds · protein-protein

Compared structures

2CYF · The Crystal Structure of Canavalia Maritima Lectin (ConM) in Complex with Trehalose and… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 2CYF · PDBe 2CYF

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