MolNFT v1 · #33861 · protein

Crystal structure of conserved hypothetical protein, TTHA0068 from thermus thermophilus HB8

2CXD: “Crystal structure of conserved hypothetical protein, TTHA0068 from thermus thermophilus HB8”. X-ray diffraction, 1 pocket (best druggability 0.39). MolNFT v1 #33861 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2CXD
Type: protein
Length: 188 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Conserved hypothetical protein, TTHA0068
UniProt: Q5SM75
Pockets: 1 · best druggability 0.39

Structure

x-ray diffraction · 1 distinct chain · 71% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Conserved hypothetical protein, TTHA0068	protein	94	71% helix, 2% strand	Q5SM75

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	52	0.39	0.82	12	empty

Interfaces

1 interface between chains.

A–B · 636 Å² buried · 6 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 modified (engineered).

Compared structures

2CXD · Crystal structure of conserved hypothetical protein, TTHA0068 from Thermus thermophilus… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5SM75
Elsewhere: RCSB PDB 2CXD · PDBe 2CXD · UniProt Q5SM75

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