MolNFT v1 · #33798 · protein
Crystal structure of thioredoxin reductase-related protein TTHA0370 from thermus thermophilus HB8
2CVJ · Thioredoxin reductase related protein: “Crystal structure of thioredoxin reductase-related protein TTHA0370 from thermus thermophilus HB8”. X-ray diffraction, 1 ligand (FAD), 1 pocket (best druggability 0.62). MolNFT v1 #33798 on…
- PDB
- 2CVJ
- Type
- protein
- Length
- 180 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Thioredoxin reductase related protein
- UniProt
- Q5SLC3
- Ligands
- FAD
- Pockets
- 1 · best druggability 0.62
Structure
x-ray diffraction · 1 distinct chain · 31% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Thioredoxin reductase related protein | protein | 180 | 31% helix, 22% strand | Q5SLC3 |
Ligands and binding sites
- FAD · Flavin-adenine dinucleotide · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 269 | 0.62 | 0.80 | 36 | FAD |
Modifications
Observed in the structure: 2 modified (engineered).
Compared structures
- 2CVJ · Crystal Structure of thioredoxin reductase-related protein TTHA0370 from Thermus… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5SLC3
- Elsewhere: RCSB PDB 2CVJ · PDBe 2CVJ · UniProt Q5SLC3
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